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There have been reports of associated paralysis and other symptoms of cerebral arterial insufficiencybut the exact relationship of these reactions to the drug has not been established.

Do not stop taking TEGRETOL without first talking to your healthcare provider.

Baseline and periodic complete urinalysis and BUN determinations are recommended for patients treated with this agent because of observed renal dysfunction.

The increased risk of suicidal thoughts or behavior with AEDs was observed as early as one week after starting drug treatment with AEDs and persisted for the duration of treatment assessedBecause most trials included in the analysis did not extend beyond 24 weeksthe risk of suicidal thoughts or behavior beyond 24 weeks could not be assessed.

Drug Reaction with Eosinophilia and Systemic SymptomsDRESSalso known as multiorgan hypersensitivityhas occurred with TegretolSome of these events have been fatal or life-threateningDRESS typicallyalthough not exclusivelypresents with feverrashand/or lymphadenopathyin association with other organ system involvementsuch as hepatitisnephritishematologic abnormalitiesmyocarditisor myositis sometimes resembling an acute viral infectionEosinophilia is often presentThis disorder is variable in its expressionand other organ systems not noted here may be involvedIt is important to note that early manifestations of hypersensitivitye.gfeverlymphadenopathymay be present even though rash is not evidentIf such signs or symptoms are presentthe patient should be evaluated immediatelyTegretol should be discontinued if an alternative etiology for the signs or symptoms cannot be established.

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